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Maternal Diet-Induced Obesity Alters Mitochondrial Activity and Redox Status in Mouse Oocytes and Zygotes

The negative impact of obesity on reproductive success is well documented but the stages at which development of the conceptus is compromised and the mechanisms responsible for the developmental failure still remain unclear. Recent findings suggest that mitochondria may be a contributing factor. How...

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Detalles Bibliográficos
Autores principales: Igosheva, Natalia, Abramov, Andrey Y., Poston, Lucilla, Eckert, Judith J., Fleming, Tom P., Duchen, Michael R., McConnell, Josie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852405/
https://www.ncbi.nlm.nih.gov/pubmed/20404917
http://dx.doi.org/10.1371/journal.pone.0010074