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TLR2 Mediates Recognition of Live Staphylococcus epidermidis and Clearance of Bacteremia

BACKGROUND: Staphylococcus epidermidis (SE) is a nosocomial pathogen that causes catheter-associated bacteremia in the immunocompromised, including those at the extremes of age, motivating study of host clearance mechanisms. SE-derived soluble components engage TLR2; but additional signaling pathway...

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Detalles Bibliográficos
Autores principales: Strunk, Tobias, Power Coombs, Melanie R., Currie, Andrew J., Richmond, Peter, Golenbock, Douglas T., Stoler-Barak, Liat, Gallington, Leighanne C., Otto, Michael, Burgner, David, Levy, Ofer
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852418/
https://www.ncbi.nlm.nih.gov/pubmed/20404927
http://dx.doi.org/10.1371/journal.pone.0010111