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Identification of SOX9 Interaction Sites in the Genome of Chondrocytes

BACKGROUND: Our previous work has provided strong evidence that the transcription factor SOX9 is completely needed for chondrogenic differentiation and cartilage formation acting as a “master switch” in this differentiation. Heterozygous mutations in SOX9 cause campomelic dysplasia, a severe skeleta...

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Detalles Bibliográficos
Autores principales: Oh, Chun-do, Maity, Sankar N., Lu, Jing-Fang, Zhang, Jiexin, Liang, Shoudan, Coustry, Francoise, de Crombrugghe, Benoit, Yasuda, Hideyo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852419/
https://www.ncbi.nlm.nih.gov/pubmed/20404928
http://dx.doi.org/10.1371/journal.pone.0010113