Interaction between Age and Obesity on Cardiomyocyte Contractile Function: Role of Leptin and Stress Signaling

OBJECTIVES: This study was designed to evaluate the interaction between aging and obesity on cardiac contractile and intracellular Ca(2+) properties. METHODS: Cardiomyocytes from young (4-mo) and aging (12- and 18-mo) male lean and the leptin deficient ob/ob obese mice were treated with leptin (0.5,...

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Detalles Bibliográficos
Autores principales: Ren, Jun, Dong, Feng, Cai, Guo-Jun, Zhao, Peng, Nunn, Jennifer M., Wold, Loren E., Pei, Jianming
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852499/
https://www.ncbi.nlm.nih.gov/pubmed/20396382
http://dx.doi.org/10.1371/journal.pone.0010085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852499/
https://www.ncbi.nlm.nih.gov/pubmed/20396382
http://dx.doi.org/10.1371/journal.pone.0010085

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