Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

Triple negative breast cancers (TNBCs) have a relatively poor prognosis and cannot be effectively treated with current targeted therapies. We searched for genes that have the potential to be therapeutic targets by identifying genes consistently over-expressed when amplified. Fifty-six TNBCs were sub...

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Detalles Bibliográficos
Autores principales: Turner, Nicholas, Lambros, Maryou B, Horlings, Hugo M., Pearson, Alex, Sharpe, Rachel, Natrajan, Rachael, Geyer, Felipe C, van Kouwenhove, Marieke, Kreike, Bas, Mackay, Alan, Ashworth, Alan, van de Vijver, Marc J, Reis-Filho, Jorge S
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852518/
https://www.ncbi.nlm.nih.gov/pubmed/20101236
http://dx.doi.org/10.1038/onc.2009.489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852518/
https://www.ncbi.nlm.nih.gov/pubmed/20101236
http://dx.doi.org/10.1038/onc.2009.489

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