Both Interaction Surfaces within Cohesin's Hinge Domain Are Essential for Its Stable Chromosomal Association

BACKGROUND: The cohesin complex that mediates sister chromatid cohesion contains three core subunits: Smc1, Smc3, and Scc1. Heterotypic interactions between Smc1 and Smc3 dimerization domains create stable V-shaped Smc1/Smc3 heterodimers with a hinge at the center and nucleotide-binding domains (NBD...

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Detalles Bibliográficos
Autores principales: Mishra, Ajay, Hu, Bin, Kurze, Alexander, Beckouët, Frédéric, Farcas, Ana-Maria, Dixon, Sarah E., Katou, Yuki, Khalid, Syma, Shirahige, Katsuhiko, Nasmyth, Kim
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852676/
https://www.ncbi.nlm.nih.gov/pubmed/20153193
http://dx.doi.org/10.1016/j.cub.2009.12.059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852676/
https://www.ncbi.nlm.nih.gov/pubmed/20153193
http://dx.doi.org/10.1016/j.cub.2009.12.059

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