Mutagenicity of New Lead Compounds to Treat Sickle Cell Disease Symptoms in a Salmonella/Microsome Assay

A series of phthalimide derivatives planned as drugs candidates to treat the symptoms of sickle cell anemia were evaluated in a mutagenicity test using strains of Salmonella typhimurium TA100 and TA102, without and with addition of S9 mixture, with the aim to identify the best structural requirement...

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Detalles Bibliográficos
Autores principales: dos Santos, Jean Leandro, Varanda, Eliana A., Lima, Lídia Moreira, Chin, Chung Man
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852868/
https://www.ncbi.nlm.nih.gov/pubmed/20386668
http://dx.doi.org/10.3390/ijms11020779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852868/
https://www.ncbi.nlm.nih.gov/pubmed/20386668
http://dx.doi.org/10.3390/ijms11020779

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