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Effects of a metalloproteinase inhibitor on osteochondral angiogenesis, chondropathy and pain behavior in a rat model of osteoarthritis

OBJECTIVE: To investigate the effects of a matrix metalloproteinase (MMP) inhibitor on joint pathology and pain behavior in the rat meniscal transection (MNX) model of osteoarthritis (OA) and evaluate which aspects of structural disease modification contribute to symptom improvement. METHODS: OA pat...

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Detalles Bibliográficos
Autores principales: Mapp, P.I., Walsh, D.A., Bowyer, J., Maciewicz, R.A.
Formato: Texto
Lenguaje:English
Publicado: W.B. Saunders For The Osteoarthritis Research Society 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853084/
https://www.ncbi.nlm.nih.gov/pubmed/20067755
http://dx.doi.org/10.1016/j.joca.2009.12.006