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Effects of a metalloproteinase inhibitor on osteochondral angiogenesis, chondropathy and pain behavior in a rat model of osteoarthritis
OBJECTIVE: To investigate the effects of a matrix metalloproteinase (MMP) inhibitor on joint pathology and pain behavior in the rat meniscal transection (MNX) model of osteoarthritis (OA) and evaluate which aspects of structural disease modification contribute to symptom improvement. METHODS: OA pat...
Autores principales: | Mapp, P.I., Walsh, D.A., Bowyer, J., Maciewicz, R.A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
W.B. Saunders For The Osteoarthritis Research Society
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853084/ https://www.ncbi.nlm.nih.gov/pubmed/20067755 http://dx.doi.org/10.1016/j.joca.2009.12.006 |
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