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The effects of adding zoledronic acid to neoadjuvant chemotherapy on tumour response: exploratory evidence for direct anti-tumour activity in breast cancer

BACKGROUND: Pre-clinical studies have demonstrated synergistic anti-tumour effects of chemotherapy (CT) and zoledronic acid (ZOL). Within the AZURE trial, designed to determine whether the addition of ZOL to neoadjuvant therapy improves disease outcomes, a subgroup received neoadjuvant CT. We report...

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Detalles Bibliográficos
Autores principales: Coleman, R E, Winter, M C, Cameron, D, Bell, R, Dodwell, D, Keane, M M, Gil, M, Ritchie, D, Passos-Coelho, J L, Wheatley, D, Burkinshaw, R, Marshall, S J, Thorpe, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853093/
https://www.ncbi.nlm.nih.gov/pubmed/20234364
http://dx.doi.org/10.1038/sj.bjc.6605604