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Phase II trial of imiquimod and HPV therapeutic vaccination in patients with vulval intraepithelial neoplasia
BACKGROUND: Vulval intraepithelial neoplasia (VIN) is a premalignant condition, which is frequently associated with type HPV16 infection, and multifocal disease has high rates of surgical treatment failure. METHODS: We report a phase II clinical trial of the topical immunomodulator, imiquimod, for 8...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853099/ https://www.ncbi.nlm.nih.gov/pubmed/20234368 http://dx.doi.org/10.1038/sj.bjc.6605611 |