Increased origin activity in transformed versus normal cells: identification of novel protein players involved in DNA replication and cellular transformation

Using libraries of replication origins generated previously, we identified three clones that supported the autonomous replication of their respective plasmids in transformed, but not in normal cells. Assessment of their in vivo replication activity by in situ chromosomal DNA replication assays revea...

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Detalles Bibliográficos
Autores principales: Di Paola, Domenic, Rampakakis, Emmanouil, Chan, Man Kid, Arvanitis, Dina N., Zannis-Hadjopoulos, Maria
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853114/
https://www.ncbi.nlm.nih.gov/pubmed/20064876
http://dx.doi.org/10.1093/nar/gkp1192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853114/
https://www.ncbi.nlm.nih.gov/pubmed/20064876
http://dx.doi.org/10.1093/nar/gkp1192

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