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Increased origin activity in transformed versus normal cells: identification of novel protein players involved in DNA replication and cellular transformation
Using libraries of replication origins generated previously, we identified three clones that supported the autonomous replication of their respective plasmids in transformed, but not in normal cells. Assessment of their in vivo replication activity by in situ chromosomal DNA replication assays revea...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853114/ https://www.ncbi.nlm.nih.gov/pubmed/20064876 http://dx.doi.org/10.1093/nar/gkp1192 |