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RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability
P21, a cyclin-dependent kinase inhibitor, plays a pivotal role in the cell-cycle regulation in response to stress stimuli. P21 expression is highly regulated through transcriptional, post-transcriptional and post-translational mechanisms. Previously, we and others showed that p21 expression is regul...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853136/ https://www.ncbi.nlm.nih.gov/pubmed/20064878 http://dx.doi.org/10.1093/nar/gkp1229 |