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Fluorescent probes for the analysis of DNA strand scission in base excision repair

We have developed fluorescent probes for the detection of strand scission in the excision repair of oxidatively damaged bases. They were hairpin-shaped oligonucleotides, each containing an isomer of thymine glycol or 5,6-dihydrothymine as a damaged base in the center, with a fluorophore and a quench...

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Detalles Bibliográficos
Autores principales: Matsumoto, Naoyuki, Toga, Tatsuya, Hayashi, Ryosuke, Sugasawa, Kaoru, Katayanagi, Katsuo, Ide, Hiroshi, Kuraoka, Isao, Iwai, Shigenori
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853145/
https://www.ncbi.nlm.nih.gov/pubmed/20110254
http://dx.doi.org/10.1093/nar/gkq022