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Novel bradykinin signaling in adult rat cardiac myocytes through activation of p21-activated kinase
Although bradykinin (BK) is known to exert effects on the myocardium, its intracellular signaling pathways remain poorly understood. Experiments in other cell types indicated that p21-activated kinase-1 (Pak1), a Ser/Thr kinase downstream of small monomeric G proteins, is activated by BK. We previou...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853422/ https://www.ncbi.nlm.nih.gov/pubmed/20154261 http://dx.doi.org/10.1152/ajpheart.01070.2009 |