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Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters
BACKGROUND: Cigarette smoking is an important risk factor for pulmonary arterial hypertension (PAH) in chronic obstructive pulmonary disease (COPD). Chymase has been shown to function in the enzymatic production of angiotensin II (AngII) and the activation of transforming growth factor (TGF)-β1 in t...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853423/ https://www.ncbi.nlm.nih.gov/pubmed/20356378 http://dx.doi.org/10.1186/1465-9921-11-36 |