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Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters

BACKGROUND: Cigarette smoking is an important risk factor for pulmonary arterial hypertension (PAH) in chronic obstructive pulmonary disease (COPD). Chymase has been shown to function in the enzymatic production of angiotensin II (AngII) and the activation of transforming growth factor (TGF)-β1 in t...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Han, Su-Xia, Zhang, Shang-Fu, Ning, Yun-Ye, Chen, Lei, Chen, Ya-Juan, He, Guang-Ming, Xu, Dan, An, Jin, Yang, Ting, Zhang, Xiao-Hong, Wen, Fu-Qiang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853423/
https://www.ncbi.nlm.nih.gov/pubmed/20356378
http://dx.doi.org/10.1186/1465-9921-11-36