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Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy

BACKGROUND: In this study we successfully created a new approach to ART in SIVmac251 infected nonhuman primates. This drug regimen is entirely based on drugs affecting the pre-integration stages of replication and consists of only two nucleotidic/nucleosidic reverse transcriptase inhibitors (Nt/NRTI...

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Detalles Bibliográficos
Autores principales: Lewis, Mark G, Norelli, Sandro, Collins, Matt, Barreca, Maria Letizia, Iraci, Nunzio, Chirullo, Barbara, Yalley-Ogunro, Jake, Greenhouse, Jack, Titti, Fausto, Garaci, Enrico, Savarino, Andrea
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853490/
https://www.ncbi.nlm.nih.gov/pubmed/20233398
http://dx.doi.org/10.1186/1742-4690-7-21