Use of the piggyBac transposon to create HIV-1 gag transgenic insect cell lines for continuous VLP production

BACKGROUND: Insect baculovirus-produced Human immunodeficiency virus type 1 (HIV-1) Gag virus-like-particles (VLPs) stimulate good humoral and cell-mediated immune responses in animals and are thought to be suitable as a vaccine candidate. Drawbacks to this production system include contamination of...

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Detalles Bibliográficos
Autores principales: Lynch, Alisson G, Tanzer, Fiona, Fraser, Malcolm J, Shephard, Enid G, Williamson, Anna-Lise, Rybicki, Edward P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853493/
https://www.ncbi.nlm.nih.gov/pubmed/20356379
http://dx.doi.org/10.1186/1472-6750-10-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853493/
https://www.ncbi.nlm.nih.gov/pubmed/20356379
http://dx.doi.org/10.1186/1472-6750-10-30

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