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Use of the piggyBac transposon to create HIV-1 gag transgenic insect cell lines for continuous VLP production
BACKGROUND: Insect baculovirus-produced Human immunodeficiency virus type 1 (HIV-1) Gag virus-like-particles (VLPs) stimulate good humoral and cell-mediated immune responses in animals and are thought to be suitable as a vaccine candidate. Drawbacks to this production system include contamination of...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853493/ https://www.ncbi.nlm.nih.gov/pubmed/20356379 http://dx.doi.org/10.1186/1472-6750-10-30 |