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APCR, factor V gene known and novel SNPs and adverse pregnancy outcomes in an Irish cohort of pregnant women

BACKGROUND: Activated Protein C Resistance (APCR), a poor anticoagulant response of APC in haemostasis, is the commonest heritable thrombophilia. Adverse outcomes during pregnancy have been linked to APCR. This study determined the frequency of APCR, factor V gene known and novel SNPs and adverse ou...

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Detalles Bibliográficos
Autores principales: Sedano-Balbás, Sara, Lyons, Mark, Cleary, Brendan, Murray, Margaret, Gaffney, Geraldine, Maher, Majella
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853494/
https://www.ncbi.nlm.nih.gov/pubmed/20214832
http://dx.doi.org/10.1186/1471-2393-10-11