Stabilizing Role of Platelet P2Y(12) Receptors in Shear-Dependent Thrombus Formation on Ruptured Plaques

BACKGROUND: In most models of experimental thrombosis, healthy blood vessels are damaged. This results in the formation of a platelet thrombus that is stabilized by ADP signaling via P2Y(12) receptors. However, such models do not predict involvement of P2Y(12) in the clinically relevant situation of...

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Detalles Bibliográficos
Autores principales: Nergiz-Unal, Reyhan, Cosemans, Judith M. E. M., Feijge, Marion A. H., van der Meijden, Paola E. J., Storey, Robert F., van Giezen, J. J. J., oude Egbrink, Mirjam G. A., Heemskerk, Johan W. M., Kuijpers, Marijke J. E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853564/
https://www.ncbi.nlm.nih.gov/pubmed/20405028
http://dx.doi.org/10.1371/journal.pone.0010130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853564/
https://www.ncbi.nlm.nih.gov/pubmed/20405028
http://dx.doi.org/10.1371/journal.pone.0010130

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