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Robust Generation of Oligodendrocyte Progenitors from Human Neural Stem Cells and Engraftment in Experimental Demyelination Models in Mice

BACKGROUND: Cell–based therapy holds great promises for demyelinating diseases. Human-derived fetal and adult oligodendrocyte progenitors (OPC) gave encouraging results in experimental models of dysmyelination but their limited proliferation in vitro and their potential immunogenicity might restrict...

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Detalles Bibliográficos
Autores principales: Neri, Margherita, Maderna, Claudio, Ferrari, Daniela, Cavazzin, Chiara, Vescovi, Angelo L., Gritti, Angela
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853578/
https://www.ncbi.nlm.nih.gov/pubmed/20405042
http://dx.doi.org/10.1371/journal.pone.0010145