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Robust Generation of Oligodendrocyte Progenitors from Human Neural Stem Cells and Engraftment in Experimental Demyelination Models in Mice

BACKGROUND: Cell–based therapy holds great promises for demyelinating diseases. Human-derived fetal and adult oligodendrocyte progenitors (OPC) gave encouraging results in experimental models of dysmyelination but their limited proliferation in vitro and their potential immunogenicity might restrict...

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Detalles Bibliográficos
Autores principales:	Neri, Margherita, Maderna, Claudio, Ferrari, Daniela, Cavazzin, Chiara, Vescovi, Angelo L., Gritti, Angela
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853578/ https://www.ncbi.nlm.nih.gov/pubmed/20405042 http://dx.doi.org/10.1371/journal.pone.0010145

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