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Sirolimus and everolimus clearance in maintenance kidney and liver transplant recipients: Diagnostic efficiency of the concentration/dose ratio for the prediction of trough steady-state concentrations
OBJECTIVES: Therapeutic monitoring of sirolimus and everolimus is necessary in order to minimize adverse side-effects and to ensure effective immunosuppression. A sirolimus-dosing model using the concentration/dose ratio has been previously proposed for kidney transplant patients, and the aim of our...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853790/ https://www.ncbi.nlm.nih.gov/pubmed/19943816 http://dx.doi.org/10.3109/03009730903291026 |