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CLOCK is suggested to associate with comorbid alcohol use and depressive disorders

BACKGROUND: Depression and alcohol abuse or dependence (AUD) co-occur in the general population more frequently than expected by chance. Alcohol use influences the circadian rhythms generated by the central pacemaker in the suprachiasmatic nucleus, and circadian rhythm alterations in turn are common...

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Detalles Bibliográficos
Autores principales: Sjöholm, Louise K, Kovanen, Leena, Saarikoski, Sirkku T, Schalling, Martin, Lavebratt, Catharina, Partonen, Timo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854106/
https://www.ncbi.nlm.nih.gov/pubmed/20180986
http://dx.doi.org/10.1186/1740-3391-8-1