Homo-binding character of LMO2 isoforms and their both synergic and antagonistic functions in regulating hematopoietic-related target genes

BACKGROUND: The human lmo2 gene plays important roles in hematopoiesis and is associated with acute T lymphocyte leukemia. The gene encodes two protein isoforms, a longer form LMO2-L and a shorter form LMO2-S. Both isoforms function as bridge molecules to assemble their partners together to regulate...

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Detalles Bibliográficos
Autores principales: Sun, Wei, Shen, Wen-Wen, Yang, Shuang, Hu, Fen, Gao, Yang, Qiao, Yu-Huan, Zhu, Tian-Hui
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854110/
https://www.ncbi.nlm.nih.gov/pubmed/20346173
http://dx.doi.org/10.1186/1423-0127-17-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854110/
https://www.ncbi.nlm.nih.gov/pubmed/20346173
http://dx.doi.org/10.1186/1423-0127-17-22

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