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Groucho-Mediated Repression May Result from a Histone Deacetylase-Dependent Increase in Nucleosome Density

Groucho (Gro) is a Drosophila melanogaster transcriptional corepressor that directly interacts with the histone deacetylase Rpd3. Although previous studies suggest that this interaction is required for repression of Gro-responsive reporters in cultured cells, the in vivo significance of this interac...

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Detalles Bibliográficos
Autores principales: Winkler, Clint J., Ponce, Alberto, Courey, Albert J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854148/
https://www.ncbi.nlm.nih.gov/pubmed/20405012
http://dx.doi.org/10.1371/journal.pone.0010166