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In Vivo Disruption of TGF-β Signaling by Smad7 in Airway Epithelium Alleviates Allergic Asthma but Aggravates Lung Carcinogenesis in Mouse

BACKGROUND: TGF-β has been postulated to play an important role in the maintenance of epithelial homeostasis and the development of epithelium-derived cancers. However, most of previous studies are mainly focused on the function of TGF-β in immune cells to the development of allergic asthma and how...

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Detalles Bibliográficos
Autores principales: Luo, Xiaolin, Ding, Qiurong, Wang, Min, Li, Zhigang, Mao, Kairui, Sun, Bing, Pan, Yi, Wang, Zhenzhen, Zang, Ying Qin, Chen, Yan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854155/
https://www.ncbi.nlm.nih.gov/pubmed/20405019
http://dx.doi.org/10.1371/journal.pone.0010149