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CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response

The centrosomal protein, CDK5RAP2, is mutated in primary microcephaly, a neurodevelopmental disorder characterized by reduced brain size. The Drosophila melanogaster homologue of CDK5RAP2, centrosomin (Cnn), maintains the pericentriolar matrix (PCM) around centrioles during mitosis. In this study, w...

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Detalles Bibliográficos
Autores principales: Barr, Alexis R., Kilmartin, John V., Gergely, Fanni
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854379/
https://www.ncbi.nlm.nih.gov/pubmed/20368616
http://dx.doi.org/10.1083/jcb.200912163