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CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response
The centrosomal protein, CDK5RAP2, is mutated in primary microcephaly, a neurodevelopmental disorder characterized by reduced brain size. The Drosophila melanogaster homologue of CDK5RAP2, centrosomin (Cnn), maintains the pericentriolar matrix (PCM) around centrioles during mitosis. In this study, w...
Autores principales: | Barr, Alexis R., Kilmartin, John V., Gergely, Fanni |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854379/ https://www.ncbi.nlm.nih.gov/pubmed/20368616 http://dx.doi.org/10.1083/jcb.200912163 |
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