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A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth

Single-nucleotide polymorphisms (SNPs) in the regulatory regions of the genome can have a profound impact on phenotype. The G3072A polymorphism in intron 3 of insulin-like growth factor 2 (IGF2) is implicated in higher muscle content and reduced fat in European pigs and is bound by a putative repres...

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Detalles Bibliográficos
Autores principales: Butter, Falk, Kappei, Dennis, Buchholz, Frank, Vermeulen, Michiel, Mann, Matthias
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854606/
https://www.ncbi.nlm.nih.gov/pubmed/20134481
http://dx.doi.org/10.1038/embor.2010.6