Homeodomain Interacting Protein Kinase 2: A Target for Alzheimer's Beta Amyloid Leading to Misfolded p53 and Inappropriate Cell Survival

BACKGROUND: Homeodomain interacting protein kinase 2 (HIPK2) is an evolutionary conserved serine/threonine kinase whose activity is fundamental in maintaining wild-type p53 function, thereby controlling the destiny of cells when exposed to DNA damaging agents. We recently reported an altered conform...

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Detalles Bibliográficos
Autores principales: Lanni, Cristina, Nardinocchi, Lavinia, Puca, Rosa, Stanga, Serena, Uberti, Daniela, Memo, Maurizio, Govoni, Stefano, D'Orazi, Gabriella, Racchi, Marco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854690/
https://www.ncbi.nlm.nih.gov/pubmed/20418953
http://dx.doi.org/10.1371/journal.pone.0010171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854690/
https://www.ncbi.nlm.nih.gov/pubmed/20418953
http://dx.doi.org/10.1371/journal.pone.0010171

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