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High-Content, Image-Based Screening for Drug Targets in Yeast

BACKGROUND: Drug discovery and development are predicated on elucidation of the potential mechanisms of action and cellular targets of candidate chemical compounds. Recent advances in high-content imaging techniques allow simultaneous analysis of a range of cellular events. In this study, we propose...

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Detalles Bibliográficos
Autores principales: Ohnuki, Shinsuke, Oka, Satomi, Nogami, Satoru, Ohya, Yoshikazu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854693/
https://www.ncbi.nlm.nih.gov/pubmed/20418956
http://dx.doi.org/10.1371/journal.pone.0010177