Cargando…

Oxpholipin 11D: An Anti-Inflammatory Peptide That Binds Cholesterol and Oxidized Phospholipids

BACKGROUND: Many Gram-positive bacteria produce pore-forming exotoxins that contain a highly conserved, 12-residue domain (ECTGLAWEWWRT) that binds cholesterol. This domain is usually flanked N-terminally by arginine and C-terminally by valine. We used this 14-residue sequence as a template to creat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruchala, Piotr, Navab, Mohamad, Jung, Chun-Ling, Hama-Levy, Susan, Micewicz, Ewa D., Luong, Hai, Reyles, Jonathan E., Sharma, Shantanu, Waring, Alan J., Fogelman, Alan M., Lehrer, Robert I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854715/
https://www.ncbi.nlm.nih.gov/pubmed/20418958
http://dx.doi.org/10.1371/journal.pone.0010181