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Enhanced Glutamatergic and Decreased Gabaergic Synaptic Appositions to GnRH Neurons on Proestrus in the Rat: Modulatory Effect of Aging

BACKGROUND: Previous work by our lab and others has implicated glutamate as a major excitatory signal to gonadotropin hormone releasing hormone (GnRH) neurons, with gamma amino butyric acid (GABA) serving as a potential major inhibitory signal. However, it is unknown whether GABAergic and/or glutama...

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Detalles Bibliográficos
Autores principales: Khan, Mohammad, De Sevilla, Liesl, Mahesh, Virendra B., Brann, Darrell W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854717/
https://www.ncbi.nlm.nih.gov/pubmed/20418960
http://dx.doi.org/10.1371/journal.pone.0010172