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Peroxisome Proliferator–Activated Receptor-γ Mediates Bisphenol A Inhibition of FSH-Stimulated IGF-1, Aromatase, and Estradiol in Human Granulosa Cells
BACKGROUND: Bisphenol A (BPA), a chemical used as a plasticizer, is a potent endocrine disruptor that, even in low concentrations, disturbs normal development and functions of reproductive organs in different species. OBJECTIVES: We investigated whether BPA affects human ovarian granulosa cell funct...
Autores principales: | Kwintkiewicz, Jakub, Nishi, Yoshihiro, Yanase, Toshihiko, Giudice, Linda C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854770/ https://www.ncbi.nlm.nih.gov/pubmed/20064783 http://dx.doi.org/10.1289/ehp.0901161 |
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