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The N-Terminal Domain of Y-Box Binding Protein-1 Induces Cell Cycle Arrest in G2/M Phase by Binding to Cyclin D1

Y-box binding protein YB-1 is a multifunctional protein involved in cell proliferation, regulation of transcription and translation. Our previous study indicated that disruption of one allele of Chk-YB-1b gene in DT-40 cells resulted in major defects in the cell cycle. The abnormalities seen in hete...

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Detalles Bibliográficos
Autores principales: Khandelwal, Payal, Padala, Mythili K., Cox, John, Guntaka, Ramareddy V.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855077/
https://www.ncbi.nlm.nih.gov/pubmed/20414334
http://dx.doi.org/10.1155/2009/243532