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Titin-Isoform Dependence of Titin-Actin Interaction and Its Regulation by S100A1/Ca(2+) in Skinned Myocardium

Titin, also known as connectin, is a large filamentous protein that greatly contributes to passive myocardial stiffness. In vitro evidence suggests that one of titin's spring elements, the PEVK, interacts with actin and that this adds a viscous component to passive stiffness. Differential splic...

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Detalles Bibliográficos
Autores principales: Fukushima, Hideto, Chung, Charles S., Granzier, Henk
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855102/
https://www.ncbi.nlm.nih.gov/pubmed/20414336
http://dx.doi.org/10.1155/2010/727239