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Titin-Isoform Dependence of Titin-Actin Interaction and Its Regulation by S100A1/Ca(2+) in Skinned Myocardium
Titin, also known as connectin, is a large filamentous protein that greatly contributes to passive myocardial stiffness. In vitro evidence suggests that one of titin's spring elements, the PEVK, interacts with actin and that this adds a viscous component to passive stiffness. Differential splic...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855102/ https://www.ncbi.nlm.nih.gov/pubmed/20414336 http://dx.doi.org/10.1155/2010/727239 |