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Suppression of mRNAs Encoding Tegument Tetraspanins from Schistosoma mansoni Results in Impaired Tegument Turnover

Schistosomes express a family of integral membrane proteins, called tetraspanins (TSPs), in the outer surface membranes of the tegument. Two of these tetraspanins, Sm-TSP-1 and Sm-TSP-2, confer protection as vaccines in mice, and individuals who are naturally resistant to S. mansoni infection mount...

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Detalles Bibliográficos
Autores principales: Tran, Mai H., Freitas, Tori C., Cooper, Leanne, Gaze, Soraya, Gatton, Michelle L., Jones, Malcolm K., Lovas, Erica, Pearce, Edward J., Loukas, Alex
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855321/
https://www.ncbi.nlm.nih.gov/pubmed/20419145
http://dx.doi.org/10.1371/journal.ppat.1000840