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Suppression of mRNAs Encoding Tegument Tetraspanins from Schistosoma mansoni Results in Impaired Tegument Turnover
Schistosomes express a family of integral membrane proteins, called tetraspanins (TSPs), in the outer surface membranes of the tegument. Two of these tetraspanins, Sm-TSP-1 and Sm-TSP-2, confer protection as vaccines in mice, and individuals who are naturally resistant to S. mansoni infection mount...
Autores principales: | Tran, Mai H., Freitas, Tori C., Cooper, Leanne, Gaze, Soraya, Gatton, Michelle L., Jones, Malcolm K., Lovas, Erica, Pearce, Edward J., Loukas, Alex |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855321/ https://www.ncbi.nlm.nih.gov/pubmed/20419145 http://dx.doi.org/10.1371/journal.ppat.1000840 |
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