Heparanase Promotes Engraftment and Prevents Graft versus Host Disease in Stem Cell Transplantation

BACKGROUND: Heparanase, endoglycosidase that cleaves heparan sulfate side chains of heparan sulfate proteoglycans, plays important roles in cancer metastasis, angiogenesis and inflammation. DESIGN AND METHODS: Applying a mouse model of bone marrow transplantation and transgenic mice over-expressing...

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Detalles Bibliográficos
Autores principales: Bitan, Menachem, Weiss, Lola, Zeira, Michael, Zcharia, Eyal, Slavin, Shimon, Nagler, Arnon, Vlodavsky, Israel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855345/
https://www.ncbi.nlm.nih.gov/pubmed/20419162
http://dx.doi.org/10.1371/journal.pone.0010135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855345/
https://www.ncbi.nlm.nih.gov/pubmed/20419162
http://dx.doi.org/10.1371/journal.pone.0010135

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