DNA Breaks at Fragile Sites Generate Oncogenic RET/PTC Rearrangements in Human Thyroid Cells

Human chromosomal fragile sites are regions of the genome that are prone to DNA breakage, and are classified as common or rare, depending on their frequency in the population. Common fragile sites frequently coincide with the location of genes involved in carcinogenic chromosomal translocations, sug...

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Detalles Bibliográficos
Autores principales: Gandhi, Manoj, Dillon, Laura W., Pramanik, Sreemanta, Nikiforov, Yuri E., Wang, Yuh-Hwa
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855398/
https://www.ncbi.nlm.nih.gov/pubmed/20101222
http://dx.doi.org/10.1038/onc.2009.502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855398/
https://www.ncbi.nlm.nih.gov/pubmed/20101222
http://dx.doi.org/10.1038/onc.2009.502

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