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Mitochondrial DNA haplogroups and risk of transient ischaemic attack and ischaemic stroke: a genetic association study

BACKGROUND: Genetic factors have a role in the pathogenesis of ischaemic stroke, but the main genes involved have yet to be defined. Mitochondrial mechanisms have been implicated in the pathophysiology of acute stroke, but the role of mitochondrial DNA (mtDNA) has not been comprehensively studied. W...

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Detalles Bibliográficos
Autores principales: Chinnery, Patrick F, Elliott, Hannah R, Syed, Anila, Rothwell, Peter M
Formato: Texto
Lenguaje:English
Publicado: Lancet Pub. Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855429/
https://www.ncbi.nlm.nih.gov/pubmed/20362514
http://dx.doi.org/10.1016/S1474-4422(10)70083-1