1-Arylsulfonyl-2-(Pyridylmethylsulfinyl) Benzimidazoles as New Proton Pump Inhibitor Prodrugs

New arylsulfonyl proton pump inhibitor (PPI) prodrug forms were synthesized. These prodrugs provided longer residence time of an effective PPI plasma concentration, resulting in better gastric acid inhibition.

Detalles Bibliográficos
Autores principales: Shin, Jai Moo, Sachs, George, Cho, Young-moon, Garst, Michael
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855619/
https://www.ncbi.nlm.nih.gov/pubmed/20032890
http://dx.doi.org/10.3390/molecules14125247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855619/
https://www.ncbi.nlm.nih.gov/pubmed/20032890
http://dx.doi.org/10.3390/molecules14125247

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