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Update on the hyper immunoglobulin M syndromes

The Hyper-immunoglobulin M syndromes (HIGM) are a heterogeneous group of genetic disorders resulting in defects of immunoglobulin class switch recombination (CSR), with or without defects of somatic hypermutation (SHM). They can be classified as defects of signalling through CD40 causing both a humo...

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Detalles Bibliográficos
Autores principales: Davies, E Graham, Thrasher, Adrian J
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855828/
https://www.ncbi.nlm.nih.gov/pubmed/20180797
http://dx.doi.org/10.1111/j.1365-2141.2010.08077.x