Effect of 4-Aminopyridine on Action Potential Parameters in Isolated Dog Purkinje Fibers

INTRODUCTION: 4-Aminopyridine (fampridine), a potassium channel blocker, has demonstrated efficacy in improving lower extremity strength and walking speed in patients with multiple sclerosis. Since in vitro electrophysiologic studies are recommended for evaluating a drug's potential to prolong...

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Detalles Bibliográficos
Autores principales: Thomas, George, Klatt, Brian, Blight, Andrew
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855834/
https://www.ncbi.nlm.nih.gov/pubmed/20428229
http://dx.doi.org/10.1111/j.1753-5174.2009.00027.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855834/
https://www.ncbi.nlm.nih.gov/pubmed/20428229
http://dx.doi.org/10.1111/j.1753-5174.2009.00027.x

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