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Effect of 4-Aminopyridine on Action Potential Parameters in Isolated Dog Purkinje Fibers
INTRODUCTION: 4-Aminopyridine (fampridine), a potassium channel blocker, has demonstrated efficacy in improving lower extremity strength and walking speed in patients with multiple sclerosis. Since in vitro electrophysiologic studies are recommended for evaluating a drug's potential to prolong...
Autores principales: | Thomas, George, Klatt, Brian, Blight, Andrew |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Inc
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855834/ https://www.ncbi.nlm.nih.gov/pubmed/20428229 http://dx.doi.org/10.1111/j.1753-5174.2009.00027.x |
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