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Metabolism and the leukemic stem cell

Acute leukemias are clonal disorders of hematopoiesis wherein a leukemic stem cell (LSC) acquires mutations that confer the capacity for unlimited self-renewal, impaired hematopoietic differentiation, and enhanced proliferation to the leukemic clone. Many recent advances in understanding the biology...

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Detalles Bibliográficos
Autores principales: Abdel-Wahab, Omar, Levine, Ross L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856035/
https://www.ncbi.nlm.nih.gov/pubmed/20368582
http://dx.doi.org/10.1084/jem.20100523